Structure:
![](/Image Library/TBJS/img/Process/Bead-Ligand Structures/ToyopearlHexyl_structure.jpg?code=cad0054f-4b33-45bd-95a6-058ff0908aa3)
TOYOPEARL Hexyl-650 resin has the highest hydrophobicity of the HIC ligands offered by Tosoh Bioscience. It is used for very hydrophilic proteins or where a low salt elution environment is required. It is useful as an early capture step or for intermediate purification.
Hydrophobicity:
Ether < PPG < Phenyl < Butyl < Hexyl
Selectivities of TOYOPEARL HIC Resins
![](/Image%20Library/TBJS/img/Process/Bead-Ligand%20Structures/HIC_selectivities.jpg?code=dee42243-9817-46a7-80ec-eec45168875a)
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Typical Dynamic Binding Capacities for Lysozyme
![](/Image Library/TBJS/img/Process/Bead-Ligand Structures/HIC_DBC_Lysozyme.jpg?code=339ae21d-fc3a-43fa-8d23-d5ae1c3c730c)
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