Structure:
TOYOPEARL PPG-600 (polypropylene glycol) resin has the second highest hydrophilicity of the HIC ligands offered by Tosoh Bioscience. It has been optimized for the purification of monoclonal antibodies and is used in intermediate purification or polishing steps. It has extremely good capacity and recovery for mAbs.
Hydrophobicity:
Ether < PPG < Phenyl < Butyl < Hexyl
Selectivities of TOYOPEARL HIC Resins
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Typical dynamic Binding Capacities for Humanized mAb
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