Structure: ![](/Image%20Library/TBJS/img/Process/Bead-Ligand%20Structures/IEX_GigaCapS_structure.jpg?code=b3dc2711-1dae-4e28-bf1e-4de4a1258213) TOYOPEARL GigaCap S-650 media is a high capacity, high resolution cation exchange resin* optimized for process scale applications, including the capture and purification of IgG as well as the polishing of monoclonal antibodies. A TOYOPEARL HW-65 polymeric bead has been chemically modified to provide a higher number of cationic binding sites for increased resin capacity. TOYOPEARL GigaCap S-650 media is stable at high linear velocities, has good pressure-flow characteristics and will withstand back pressures up to 3 bar. The higher capacity and back pressure stability of TOYOPEARL GigaCap S-650 resin creates opportunities for increased throughput in downstream cation exchange purification steps. *TOYOPEARL GigaCap resins are designed specifically for packed bed use. | IgG breakthrough curves at various flow rate ![](/Image Library/TBJS/img/Process/CEX/IEX_GigaCapS_fig1.jpg?code=83416513-d8bd-41ca-a315-38dec73cf4f2) Excellent Pressure-Flow Properties ![](/Image Library/TBJS/img/Process/CEX/IEX_GigaCapS650S_fig1.jpg?code=b74dc058-157a-4779-b65d-2d12ef22a0f0) High DBC at Increased Linear Velocities ![](/Image Library/TBJS/img/Process/CEX/IEX_GigaCapS650S_fig2.jpg?code=8c548872-c8b0-410d-bcfe-9b9986556801) |