Mixed Mode Chromatography | https://separations.asia.tosohbioscience.com

Structure:

TOYOPEARL MX-Trp-650M is a high capacity mixed-mode resin used for the purification of monoclonal antibodies and other proteins. This multi-modal resin maintains dynamic binding capacity (DBC) at elevated feedstock and buffer conductivities.

In addition to fast binding and elution kinetics, TOYOPEARL MX-Trp-650M minimizes the amount of WFI needed for either feedstock dilution during capture or column elution further downstream, leading to lower in-process pool volumes and higher throughput.

TOYOPEARL MX-Trp-650M maintains a high DBC even after extended CIP (clean in place) cycles using 0.5 mol/L NaOH.

Maintains DBC post CIP with 0.5 mol/L NaOH

Maintains DBC at Higher Conductivities

Excellent Elution Kinetics

Literature :

• Catalog

• Instruction Manual

TOYOPEARL MX-Trp-650M

Pore size (mean)	100 nm
Particle size (mean)	75 µm
Pressure rating	0.3 MPa
Shipping buffer	20% ethanol
pH stability	3 - 13

P/N	Description	Container size	Particle size	Adsorption capacity
0022818	Toyopearl MX-Trp-650M	100 mL	50 - 100 µm	≥ 75g IgG/L gel